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Herpes Zoster



Sinonim
          Shingles
          Cacar saraf ; Cacar ular (Tjoa)
Definisi
          Radang kulit akut ditandai lesi khas vesikel berkelompok di atas dasar kulit eritematus, sepanjang persarafan sensorik sesuai dematom; Unilateral
Etiologi
          Virus Varisela-Zoster
          Penularan secara aerogen
Patogenesis
3 teori ::
1. Reinfeksi : imunitas ↓
2. Reaktivasi: virus laten g Tumor/ TBC
3. Infeksi langsung g dermatom

Klinis
          Prodromal 3 – 5 hari, lesu ; subfebril
          Hiperestesi, panas & nyeri tusuk-tusuk g dermatom
          Efl. eritema + papel à 7 hari à vesikel berkelompok menjadi
          Sp bula      pecah                  Erosi
                                                      Ulkus
          K.G.B biasanya membesar
          Predileksi :
        Muka & badan
        Unilateral
        Kadang bilateral g Herpes Zoster Aberantes
          KHAS !!!!
      Lesi dalam 1 dermatom = POLIMORF
      Lesi dalam 1 kelompok  = MONOMORF

Bentuk Klinis
          H.Z. Varicelliformis : H.Z + varisela = H.Z. Generalisata / Diseminata
          H.Z. Haemorhagic
        Orang tua + keadaan umum jelek
        Penyakit kronis (leukemia, limfoma)
          H.Z. Thoracalis : TERSERING
          N. Trigeminus :
          H.Z. Opthalmicus à MRS
          H.Z. Maxillaris
          H.Z. Mandibularis
          N. Facialis
          C2 ; L2
Ganglion Geniculatum (N.VII)
          H.Z. Oticus = RAMSAY HUNT Syndr.
          Antara lain:                  
q  Vesikel liang telinga luar & palatum    post & uvula
q  Paralisis N. VII (sensoris)
q  Lagofthalmus
q  Tinitus, vertigo, pendengaran ↓
Diagnosis
      Gambaran klinis khas g mudah
Diagnosis Diferensial
        Dermatitis kontak
        Herpes simpleks zosteriformis
Laboratorium
        TZANCK test Å: kerokan dasar vesikel + giemza g sel datia berinti banyak
Therapy
§  Umum : istirahat, simtomatis, cegah infeksi sekunder, obat anti virus
§  Lokal : Salicyl talc, Zalf antibiotik, Desinfektan
Prognosis
          Baik ;
          Orang tua lemah g V

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